Fefu and Her Friends is recognized as a feminist play for its all-female cast, central ideas of gender roles, and its bold deviations from conventional stage presentation and audience involvement. Fornés divides the stage into a kitchen, bedroom, study, and lawn, and a short scene in each area is acted out with a fourth of the audience closely viewing each part. The groups of spectators rotate until they have seen all four scenes. These individual scenes highlight conflict in all of the women's lives and thus illustrate a more communal feminist struggle than "the typical feminist approach of the early days of the second wave of the movement which emphasized the existence and the rights of the individual woman."

Fornés uses the play as representation of the struggle of women against the female stereotype. Any interactions with male characters are done offstage and no established male characters are seen to portray how women behave when not in the presence of men.